. Berberine does not increase caloric expenditure. My understanding would be that tyrosine hydroxylase is the enzyme that breaks down dopamine. 428 g/mol and the chemical formula C21H25NO4. It may also help with some symptoms associated with the common cold and may also be used for sedating people who are agitated or anxious. What Is Berberine? How Does Berberine Work? 11 Berberine Benefits. Several years later in 2009, a longer-acting format of the medication called 'Invega Sustenna' was also approved. Everyone who experiences weight loss from berberine is due to it’s appetite suppressant effects, which is probably downstream of its effects in blood glucose levels. 12 These increases in biogenic amine levels are attributed to the inhibition of monoamine oxidase by berberine. It can also help with perimenopausal mood symptoms. Answer (1 of 11): Odd as it seems, I think stimulants would be a possibility. Iron and green tea. It is made in small amounts by the human body but is also acquired through food and supplements. protein foods (like scrambled eggs with spinach) 3. The phenylalanine-tyrosine-dopa-dopamine pathway provides dopamine to the brain. In two separate studies, 34-46 percent of men had a positive outcome. It is the process of utilizing your genetic make-up, lab results, symptoms and available scientific information to manage your health. Key findings Berberine has multiple neuropharmacological properties, such as neuroprection, anti-neuronal apoptosis, improvement of cerebral microcirculation and anti-Alzheimer's disease, and so on. (10) This was thought to the due to berberine’s inhibition of monoamine oxidase-A, the enzyme which degrades norepinephrine and serotonin (5-HT). (10) This was thought to the due to berberine's inhibition of monoamine oxidase-A, the enzyme which degrades norepinephrine and serotonin (5-HT). 5 hours a sleep to regenerate. Berberine is a chemical found in some plants like European barberry, goldenseal, goldthread, Oregon grape, phellodendron, and tree turmeric. The combination of Adderall and Cymbalta may also trigger serotonin syndrome development, a rare disorder. Aug 06, 2020 · Safety precautions and possible side effects. Its seemingly potent ability to reduce blood sugar rivals that of some anti-diabetic drugs. 1:18 · Controlling Your Dopamine For Motivation, Focus & Satisfaction | Episode 39 - Andrew Huberman view episode. A merica is beginning —far too late and far too slowly— to get some kind of a grip on deaths and harms involving illicit fentanyl and other opioids. Dale Bredesen and his team at MPI Cognition. Rat models of PD were prepared by 6-OHDA lesions in the ipsilateral sides, and then were treated with berberine (5 and 15 mg/kg) and/or l-DOPA (10 mg/kg) once daily for. Caffeine increases dopamine levels in the same way. Berberine is an isoquinoline alkaloid compound most prevalent in several plant species, including Berberis vulgaris L. Those furthest to the right (OPC 4392 and bifeprunox) seem to be too activating and to have too much of a dopamine "kick"—more. a random recommendation from people on reddit or. Rhonda also gives. Bottom line: Berberine helps reduce both generalized inflammatory levels and hepatocyte inflammation. Facet Joint Pain Relief Uk Aliminum Foil Pain Relief Chinese Wikipedia The ideal cream will provide quick and powerful. Chronic administration of berberine (5 mg/kg, ip) for 15 days significantly increased the levels of norepinephrine (29%), serotonin (19%) as well as dopamine (52%). Coconut oil is very heat stable, so it's an ideal oil to use for frying and cooking. Berberine is considered an alkaloid that’s extracted from a variety of plants that includes Berberis, hence the name ‘berberine’. These include. sexual dysfunction. Examine Database Research feed Berberine is most often used for. p-tyramine which CYP2D6 metabolizes into dopamine in the brain and liver. Taking ashwagandha with herbs or supplements that have sedative properties can enhance both adverse and therapeutic effects. Emil Nutrition 200 MG 5-HTP Plus Formula for Mood, Stress, and Sleep - 60 Vegan Capsules, 30 Servings on Amazon. In mice, berberine increases norepinephrine, serotonin, and dopamine. gov 143 44 r/Nootropics Join • 14 days ago Obesity Is Now the Top Modifiable Dementia Risk Factor in the US (July 2022) jamanetwork. This may be contingent upon other defects, but the CBS mutation is definitely responsible for the elevation in taurine, ammonia, sulfites, and hydrogen sulfide. Nurture and convert customers. Ginseng · 10. If it's helping you produce more dopamine, or increase your overall dopamine levels, then we’ll say that it works. Risks and Side Effects. Jul 31, 2020 · Berberine (BBR), a natural isoquinoline alkaloid, is known as an outstanding biologically active natural product. Betaine for bodybuilding improves hydration, stimulates water-based pumps, improves power, and supports protein synthesis. O CETCC é a Escola de Pós-graduacão em Terapia Cognitivo-comportamental de Beck que mais forma especialistas na abordagem, atualmente Which is essentially why I like ashwagandha as well, except I ascribe ashwagandha's "chill" to its adaptogenic activation of GABA receptors and potential antioxidant. If they did he didn’t mention it. It has lipotropic (fat-reducing) effects, so it has been shown to produce significant improvements in treating fatty liver disease by helping the liver process and remove fats. There is ample evidence that moderate caffeine intake. ) Most of the time, berberine supplements include other botanicals and herbs aimed at treating a given condition. Responsible for transmitting signals between the nerve cells of the brain, dopamine is often called a chemical messenger. It is a precursor of nitric oxide that relaxes and dilates blood vessels, thereby allowing more nutrients to enter your muscles during workouts. Turmeric also has hypercholesteremic effect as. Rigorously Tested for Purity and Identity. There is no legal use for it Your body makes it, and your nervous system uses it to send messages between nerve cells Increase your dopamine levels with the right foods Dopamine is the ‘happy’ hormone that induces a feeling of general well-being Read on to know how to boost it naturally Welcome to r/DopamineDetox, reddit's. Aug 17, 2022 · This enzyme catalyzes the bioconversion of L-Tyrosine into the dopamine precursor L-DOPA. Mar 29, 2013 · The effects of berberine on long-term administration of l-DOPA in 6-hydroxydopamine (6-OHDA)-lesioned rat model of Parkinson’s disease (PD) were investigated. Berberine in Huan-Bai and Amur Cork-Tree can increase brain-derived neurotrophic factor ( BDNF ). It's not a stimulant. Huang Bai can. Studies over the past two years suggest a potential role for L-theanine in supporting cognitive function. Toniq Berberine. NIRKO mice also exhibit increased levels of monoamine oxidase A and B (MAO A and B) leading to increased dopamine turnover in these areas. This explains why, after consuming a big cup of coffee, your hands get cold, your muscles grow tense, you feel excited and your heart beats faster. Neuroinflammation (inflammation of the brain) is linked to many degenerative brain diseases such as Parkinson's Disease (PD) and Dementia. You should also use caution when combining it with natural blood-thinning supplements like ginkgo biloba. Very interesting supplement. Preliminary research shows that it may improve thyroid levels in those with hypothyroidism. Rewards like sex, money, drugs and novel situations all cause the release of dopamine in the reward circuit of the brain, a region buried deep beneath the cortex. " As shown in Table 1, after 8 weeks of BBR therapy, blood dopa/dopamine was elevated (dopa, NS, +17%↑. It is often used for diabetes or cholesterol issues, and some evidence. Also called the Berberine (Oregon Grape) Berberine is a natural WNT pathway inhibitor (48-51) Berberine is actually patented as a targeted cancer stem cell therapy. This plant-based protein contains the 9 essential amino acids in an alkaline form. Berberine supplements have been found to increase dopamine concentrations in some areas of the brain. Available coupons. Promethazine is available by mouth in syrup or tablet dosage forms, as a rectal suppository, or by injection into a muscle. There's a link between anxiety, reaction to stress, and the brain's most fundamental function, maintaining cognition. Moreover, BER could induce Nrf2 expression but inhibits p38-MAPK and. It is the process of utilizing your genetic make-up, lab results, symptoms and available scientific information to manage your health. Nov 02, 2021 · The chemical has already been discussed in another thread (see 1st link in References below), so this is just the announcement that it is now available for purchase. 34 Dopa and dopamine (dopa/dopamine) are low-molecular-weight compounds that could be detected in biological samples quantitatively and. Log In My Account gq. Moreover, BER could induce Nrf2 expression but inhibits p38-MAPK and. Aug 17, 2022 · This enzyme catalyzes the bioconversion of L-Tyrosine into the dopamine precursor L-DOPA. More Links: Lab And Tests. In this process, tyrosine hydroxylase (TH) is the rate-limiting enzyme that hydroxylates tyrosine and generates levodopa (L-dopa) with tetrahydrobiopterin (BH<sub>4</sub>) as a coenzyme. The phenylalanine-tyrosine-dopa-dopamine pathway provides dopamine to the brain. Kulkarni et al showed that acute administration of berberine (5 mg/kg, i. Reference: Lee B, Shim I, Lee H, Hahm DH. Huang Bai can. It also reduces post-workout pain by producing natural analgesics in the body. This explains why, after consuming a big cup of coffee, your hands get cold, your muscles grow tense, you feel excited and your heart beats faster. I ordered Glycox 500 (500mg) based on Amazon reviews that specified decreases in BG. Aside from this, the purity and supplement design is good but not the absolute best. 164 reviews. Rat models of PD were prepared by 6-OHDA lesions in the ipsilateral sides, and then were treated with berberine (5 and 15 mg/kg) and/or l-DOPA (10 mg/kg) once daily for 21 days. 19, 20 Berberine can also inhibit the release of NE via activation of. Log In My Account hs. It also aids in decision making and sleep regulation (1, 2). From protein powders and probiotics to collagen & keto diet basics, The Vitamin Shoppe has all your best-self-supplies. Mucuna Pruriens, or Velvet Bean, is a bean that grows from vines in several places worldwide. As the amount of serotonin in the brain increases to dangerous levels, you might feel disoriented or irritable, experience muscle twitches or rigidity, feel abnormally warm, and begin to sweat profusely. Berberine is a unique and powerful dietary supplement with nootropic benefits. It supports muscle gain, enhances blood flow, and increases your strength. Plays an important role in. Having enough GABA at the end of the day is important for turning down brain activity and preparing us for sleep. Here, we show that oral berberin. Before bed: 500mg Sensoril, 500mg schisandra, 750mg lemon balm extract, 200mg apigenin. Inositol supplements seem to be well-tolerated by most people. Regular Berberine supplements are weak compared to this. He transitioned from the suspicion of low dopamine to talking about Abilify. Berberine is a unique and powerful dietary supplement with nootropic benefits. Berberine HCL 400mg from Haya Labs thanks to its energy-enhancing action, supporting insulin sensitivity, has. Dopamine is a type of neurotransmitter. A study in 20 athletes showed that daily yohimbine supplementation reduced body fat levels from 9. This may be contingent upon other defects, but the CBS mutation is definitely responsible for the elevation in taurine, ammonia, sulfites, and hydrogen sulfide. Collagen Peptides. Dopamine is a type of neurotransmitter. Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the selective loss of nigral dopaminergic neurons and a reduction in striatal dopaminergic fibers, which result in tremors, rigidity, bradykinesia and gait disturbance. Responsible for transmitting signals between the nerve cells of the brain, dopamine is often called a chemical messenger. 6mg/kg equivalent to humans, but. Taurine is an amino acid and somewhat harmless in the body, but the others are dangerous toxic substances. Jun 07, 2018 · Berberine [Thorne Research] 500 MG; 1 Cap Morning, 1 Cap Afternoon then 1 Cap Evening about 6:30 PM. Furthermore, it’s often compared to creatine. National Library of Medicine. The 7,8 - DHF ties the whole stack together by promoting neuroplasticity and dialing in. It has a high L-Dopa content, among various other phytochemicals, and is generally taken as an extract according to L-Dopa dose. Berberine upregulates BDNF (brain-derived neurotrophic factor). ( Curcuma longa ). It is also widely available as a dietary supplement. Parkinson's disease (PD) is a progressive neurodegenerative disease that comprises a range of motor and non-motor symptoms. Have a team dedicated to security & privacy. Better blood sugar control than regular Berberine. The concurrent use of Adderall and Cymbalta can result in increased anxiety, restlessness, and racing thoughts. Coconut Oil. There's a link between anxiety, reaction to stress, and the brain's most fundamental function, maintaining cognition. Of course, they also ruin your life so that’s not an option. Berberine was extracted from slices of Berberis thunbergii, cut into various sizes (#1-#4), with water and methanol at 37°. Some testosterone-boosting examples of zinc-rich foods are: Oysters, which have a very high amount of zinc. All of Emerson’s brands meet federal current Good Manufacturing Practices (cGMPs). Oct 10, 2020 · Let's learn more about this ingredient and how it could help with weight loss, Type 2 diabetes, heart health, and more. 3 Best Berberine Supplement – [2021] Review. Berberine was found to be an antagonist at both dopamine D1- and D2-like receptors and ameliorates the development of experimentally induced colitis in mice. rosea is a perennial plant with a thick rhizome and yellow, fragrant flowers. Jun 14, 2019 · Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the selective loss of nigral dopaminergic neurons and a reduction in striatal dopaminergic fibers, which result in tremors, rigidity, bradykinesia and gait disturbance. These results suggested that berberine aggravated 6-OHDA-induced cytotoxicity in PC12 cells, and led to the degeneration of dopaminergic neuronal cells in the. . It plays a variety of roles actually, including the most important which is to grow new brain cells. Berberine is extremely safe and well-tolerated. Anti-androgens may protect against severe COVID-19 outcomes: results from a prospective cohort study of 77 hospitalized men. The metabolic effects of inositol may not be appropriate for everyone. Avoid or limit alcohol intake when you're stressed. Anti-androgens may protect against severe COVID-19 outcomes: results from a prospective cohort study of 77 hospitalized men. The addition of valerian root extract to the treatment cause a significant improvement in the anxiety felt by the patients including tension, anxiety and poor sleep quality. It also. This episode serves as a sort of “Dopamine Masterclass”. Berberine vs Metformin 115 100 r/Nootropics Join • 1 mo. Responsible for transmitting signals between the nerve cells of the brain, dopamine is often called a chemical messenger. Buy vitamins, supplements, herbs & more. It helps support the detoxification process, assists with cellular energy, and supports intestinal and brain health, all important factors in OCD. It might help strengthen the heartbeat, which could benefit people with certain heart conditions. The structure supports two key features of the NCS "dopamine-first" mechanism: the binding of dopamine catechol to Lys-122 and the position of the carbonyl substrate binding site at the active site entrance. Buy Now. Limitless Life Nootropics Bromantane Reddit. Discussion of nootropics and cognitive enhancers. TGF-b is a cytokine that seems to affect the growth, proliferation, and repair of many cell types. What is often the case in these scenarios is that a healthcare. Berberine is a well-studied supplement with many beneficial possibilities. Caffeine · 9. About Reddit Turmeric Adderall. Perfect addition to a healthy aging program *. Here, we show that oral berberin. Berberine ranks quite well in terms of safety, yet it’s not risk-free. Absorption Enhancers: Applications and Advances. I ordered Glycox 500 (500mg) based on Amazon reviews that specified decreases in BG. National Center for Biotechnology Information. 2022 Author:. Aug 17, 2022 · This enzyme catalyzes the bioconversion of L-Tyrosine into the dopamine precursor L-DOPA. Looking for an liver supplement? Our Anti-Alcohol Complex provides nutrients - grape seed, barley grass and milk thistle extracts- to support detoxification and a healthy liver in times when we are exposed to environmental stresses, and the liver neutralize potential toxins. " As shown in Table 1, after 8 weeks of BBR therapy, blood dopa/dopamine was elevated (dopa, NS, +17%↑. Here, we show that oral berberine (BBR) might supply H•through dihydroberberine (reduced BBR produced by bacterial nitroreductase) and promote the production of BH4from dihydrobiopterin; the increased BH4enhances TH activity, which accelerates the production of l-dopa by the gut bacteria. Rat models of PD were prepared by 6-OHDA lesions in the ipsilateral sides, and then were treated with berberine (5 and 15 mg/kg) and/or L-DOP. 187 votes, 55 comments. This enzyme catalyzes the bioconversion of L-Tyrosine into the dopamine precursor L-DOPA. Aging = Less Dopamine. However, scientists believe that, in excess, TGF-beta may lead to wound "over-healing," which causes scarring and keloids. Oregano oil health benefits include fighting bacterial infections, fungal infections, digestive problems, inflammatory conditions and tumor growth. It supports muscle gain, enhances blood flow, and increases your strength. Free Shipping Over $70. videos caseros porn, 247 transfer portal rankings
Polygala tenuifolia kicks things off with a balanced stimulation, which then hands things over to Berberine which helps kick that focused stimulation up a notch. . Berberine dopamine reddit
Drug Enforcement Administration (DEA) classifies. Uridine is a cofactor in many processes in the body. In addition to helping your memory, Bioperine may also boost some of your other executive functions. Besides, BER could repress inflammatory markers tumour necrosis factor-α, interleukin-6 and IL-1β, as well as prostaglandin E2, inducible nitric oxide synthase and cyclooxygenase-2. It's more likely to be found in women some of whom aren't diagnosed until. Bottom line: Berberine helps reduce both generalized inflammatory levels and hepatocyte inflammation. This massive supplement manufacturer clearly sees that the nootropics market has a real future, so it wants to get in on the action With PowderCity For instance, there is the possibility to buy Adderall 20 mg online and buy Adderall 30mg online Opiate tolerance and the subsequent withdrawal from opiates such as heroin,. Mood elevator and anti-depressant ( Rubiaceae ) native to the formation of ATP, the did!. Digestive upset is more likely at higher doses Nac reddit adhd Hydrogen Peroxide In Car Battery -Maximum dose: 200 mg/day 11 to 17 years:-Initial dose: 25 mg orally once a day at bedtime-Maintenance dose: 25 to 300 mg orally per day-Maximum dose: 300 mg/day Comments: The dose may be increased in 25 mg increments every 4 to 7 days, as tolerated. Dec 19, 2020 · Besides, BER could repress inflammatory markers tumour necrosis factor-α, interleukin-6 and IL-1β, as well as prostaglandin E2, inducible nitric oxide synthase and cyclooxygenase-2. Berberine may interfere with the absorption of tetracycline and related antibiotics. Berberine has many other mechanisms of action that are of interest but are less studied at the moment. Search: Reddit Healthy Dopamine Reddit Dopamine Healthy gmc. I ordered Glycox 500 (500mg) based on Amazon reviews that specified decreases in BG. She’s been taking 1 cap in am w/breakfast, and 2 caps w/dinner; total 1500 mg/day. Adderall can be highly addictive and cause a variety of side effects. When large amounts have been given to mice . Perfect addition to a healthy aging program *. In Canada, you may report side effects to Health Canada at 1-866-234-2345. Coffee is a staple in many people's lives due to its "pick-me-up" qualities and reported health benefits. While asleep, GABA actively turns off many areas of the brain to allow for rest and recovery. Mark’s Picks. This is because duloxetine can increase the effects of Adderall. L-Dopa is a treatment for Parkinson's disease, and researchers seek to evaluate its effects compared with pharmaceutical L. Collagen Peptides. Answer (1 of 7): Depends on what you mean by increase. Just had a licensed dietitian tell me bulking is "wrong" and you gain muscle by "eating less calories" 🙃. It is very good for your overall health but there. High blood pressure and weight gain often go hand in hand. The addition of valerian root extract to the treatment cause a significant improvement in the anxiety felt by the patients including tension, anxiety and poor sleep quality. As the amount of serotonin in the brain increases to dangerous levels, you might feel disoriented or irritable, experience muscle twitches or rigidity, feel abnormally warm, and begin to sweat profusely. V. We and our partners store and/or access information on a device, such as cookies and process personal data, such as unique identifiers and standard information sent by a device for personalised ads and content, ad and content measurement, and audience insights, as well as to develop and improve products. BBR increased dopa/dopamine production in the gut microbiota in vivo. More Links: Lab And Tests. A herbal medicine used in the treatment of addiction mimics the action of amphetamine on in vitro rat striatal dopamine release - 2002 pubmed. Nurture and convert customers. Dopamine is most notably involved in helping us feel pleasure as part of the brain’s reward system. Each serve of Vital All-In-One (Vital Greens) contains 1,000mg or 1 gram of Vital Pea Protein. " (2016) lifeextension 400 73 r/Nootropics Join. L-Tyrosine - 500mg Throne Research. Moreover, BER could induce Nrf2 expression but inhibits p38-MAPK and. Limitless Life Nootropics Bromantane Reddit. Berberine (BBR), a natural isoquinoline alkaloid, is known as an outstanding biologically active natural product. I ordered Glycox 500 (500mg) based on Amazon reviews that specified decreases in BG. Polygala tenuifolia kicks things off with a balanced stimulation, which then hands things over to Berberine which helps kick that focused stimulation up a notch. Aspirin – ( Amazon) Take 300mg with a meal. Side effects, if any, tend to be mild and may include nausea, stomach pain, tiredness, headache, and dizziness. An extensive search in electronic databases (PubMed, Scopus, Embase, Web of Sciences and Science Direct) was used to identify the clinical trials on B. Here, get critical information on this popular ADD treatment and its common usage guidelines, noted side effects, and typical benefits. Feb 24, 2021 · The phenylalanine-tyrosine-dopa-dopamine pathway provides dopamine to the brain. To exacerbate this, people who are prescribed controlled substances used to treat attention deficit and hyperactivity disorders (ADD/ADHD) are facing a crippling shortage of. Milk thistle with berberine (600mg 1 daily for liver health and increased insulin sensitivity) Vitamin D with K (5000 IU k2 helps increases bioavailability of D, i try to take it with fat as well since that helps bioavailability ) Magnesium glycinate (600mg) Zinc + copper (15mg might increase this since NAC can chelate zinc and copper). Berberine is a compound that can be extracted from many herbs. What are the uses of Berberine? · Lowers blood sugar levels · Reduces insulin resistance · Helps in weight loss · Soothes canker sores · Lowers blood cholesterol . While asleep, GABA actively turns off many areas of the brain to allow for rest and recovery. If it's helping you produce more dopamine, or increase your overall dopamine levels, then we’ll say that it works. 12 These increases in biogenic amine levels are attributed to the inhibition of monoamine oxidase by berberine. Studies over the past two years suggest a potential role for L-theanine in supporting cognitive function. This episode serves as a sort of "Dopamine Masterclass". Paladini’s focus on dopamine began with treatments for drug addiction, which disturbs the normal “reward system” in the brain If the specific drug a person is using is affecting dopamine, then one could deduce what bodily functions withdrawal will effect A brief, 12 question test to determine if you may have an issue. For example, people with diabetes might buy a berberine supplement with cinnamon, which has been associated with lowering blood sugar. Reddit pharmacy provides information about prescription medications that are taken to treat various kinds of diseases. : Extraction of Berberine from Berberis thunbergii. Increase metabolic rate or energy expenditure via increased beta adrenergic (adrenaline) activity. Read on to learn about how the drug affects dopamine, another important chemical in the body. Folate as a nootropic is involved in the synthesis of dopamine, epinephrine, norepinephrine and serotonin. Research and clinical experience has shown Berberine to be as effective in controlling diabetes as the prescription drug metformin. L-Dopa is a first-line drug to treat PD, as it could cross the blood–brain barrier and then through the action of DDC be converted into dopamine, which there is a shortage in PD. From protein powders and probiotics to collagen & keto diet basics, The Vitamin Shoppe has all your best-self-supplies. xt; vc. My daily (M-F) stack consists of: Right when I wake up - 1 OptimALA, 1-2g ALCAR, 20mg micro zinc, 1 cap of immuse, and alternate CoQH-CF and CoQsol-CF. In this post, you are going to learn about the most dangerous fenugreek side effects and how you can avoid them. National Center for Biotechnology Information. Berberine, geleneksel Çin tıbbında kullanılan çeşitli bitkilerden alınan alkaloiddir. Anti-cancer activity. substance: route of administration: (optional) in combination with: (optional) in combination with: (optional) or author collection: author gender: intensity: to: experience category:. Therefore it can cause or cure a lot of gut distress depending on what condition your gut is in. Thanks to its prolactin-lowering and calming effects on the nervous system, vitex can relieve premenstrual symptoms such as irritability, fluid retention, and breast pain. Dopamine, a feel-good chemical, has a direct impact on your health and mental health. It is a blend of magnesium caprylate, berberine, and. Objectives This review summarizes recent research on the neuropharmacological and pharmacokinetic properties of berberine, an isoquinoline alkaloid extracted from Coptidis rhizoma. Jan 29, 2022 · Andrew can have times like this just like everyone else and has supplements that he takes as part of his regimen that specifically address cognitive function. Reddit is an open source, crowdsourcing social news network where users can post and read posts. The as prepared nanoparticles were then surface functionalized by dopamine polymer to make them water dispersible. 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